Uma Brothers LBS Marg, Mumbai, Maharashtra

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GST Number : 27AGPPS8689E1ZF
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  • ZUCLOPENTHIXOL

    ZUCLOPENTHIXOL

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    We are offering zuclopenthixol. Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at d1 and d2 dopamine receptors. Zuclopenthixol, also known as zuclopentixol or zuclopen- thixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at d1 & d2 dopamine receptors. Major brands of zuclopenthixol are cisordinol, acuphase, and clopixol. This drug is a liquid. This compound belongs to the thioxanthenes. These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing oxygen atom with a sulfur atom. Known drug targets of zuclopenthixol include 5-hydroxytryptamine receptor 2a, d (1b) dopamine receptor, d (2) dopamine receptor, d (1a) dopamine receptor, and alpha-1a adrenergic receptor. synonyms: 2-[4-[(3z)-3-(2-chlorothioxanthen-9-ylidene) propyl] piperazin-1-yl] ethanol cas number: 53772-83-1, mol. Formula: c22h25cln2os, mol.weight: 400.96 zuclopenthixol is a pale yellow low melting solid. It is slightly soluble in water with melting point of 50°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • zonisamide

    zonisamide

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    We are offering zonisamide. Zonisamide is an anti-epileptic agent. The mechanism action of zonisamide is as a carbonic anhydrase inhibitor & p-glycoprotein inhibitor. The physiologic effect ofzonisamide is by means of decreased central nervous system disorganized electrical activity. The chemical classi- fication of zonisamide is sulfonamides. Zonisamide is a sulfonamide derivative with an anticonvulsant property the exact mechanism of action remains to be elucidated. zonisamide appears to block sodium & calciumchannels, thereby stabilizing neuronal membranes and suppressing neuronal hyper-synchronization. Although zonisamide shows affinity for the gamma-aminobutyric acid (gaba)benzodiazepine receptor ionophore complex, it does not potentiate the synaptic activity of gaba. In addition, this agent also facilitates both dopaminergic and serotonergic neurotransmission. synonyms: (1, 2-benzoxazol-3-ylmethanesulfonamide cas number: 68291-97-4, mol. Formula: c8h8n2o3s, mol.weight: 212.23 zonisamide is an off-white solid powder. It is soluble in water (10 mm), dmso (100 mm), 1.1eq naoh (100 mm), ethanol (25 mm), methanol, and ethyl acetate with melting range of 162°c to 167°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Zinc Sulfate Monohydrate

    Zinc Sulfate Monohydrate

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    We are offering zinc sulfate monohydrate. Zinc sulfate monohydrate can be used in electrolytes for zinc plating. It can be used as a mordant in dyeing. It can also be used in medicine as an astringent and emetic. Zinc sulfate monohydrate can be used to supply zinc in animal feeds, fertilizers, and agricultural sprays. synonyms: sulfuric acid zinc salt monohydrate;zinc sulfate-1-hydrate;zinc sulfate monohydrate;zinc sulfate;zinc sulphate h2o;zinc sulphate monohydrate;sulfuricacid,zincsalt(1:1),monohydrate;zincfertilizer cas number: 7446-19-7, mol. Formula: h2o5szn, mol.weight: 179.47 zinc sulfate monohydrate is a white powder or granules. It is soluble in water with melting point of 100°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • zaleplon

    zaleplon

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    We are offering zaleplon. Zaleplon is a gamma-aminobutyric acid a receptor agonist. The mechanism of action of zaleplon is as a gaba an agonist. The physiologic effect of zaleplon is by means of central nervous system depression. Zaleplon is a nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative anxiolytic & muscle relaxant properties. zaleplon interacts with the gamma-aminobutyric acid (gaba) -a receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of gaba. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the gaba-achloride ion channel receptor complex and potentiates t-butyl-bicyclophospho- rothionate (tbps) binding. synonyms: n-[3-(3-cyanopyrazolo [1, 5-a] pyrimidin-7-yl) phenyl]-n-ethylacetamide cas number: 151319-34-5, mol. Formula: c17h15n5o, mol.weight: 305.33 zaleplon is an off-white powder. It is easily soluble in methanol (sparingly), and dmso with melting range of 186°c to 187°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Voglibose

    Voglibose

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    We are offering voglibose. Voglibose is a valiolamine derivative & inhibitor of alpha-glucosidase with antihyperglycemic activity. Voglibose binds to & inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides & disaccharides into- glucose & other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose & decreases the rise in post- prandial blood glucose levels. Voglibose is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus. Voglibose is orally active maltase-glucoamylase (α-glucosidase) inhibitor (ic50 values are 3.9 & 6.4 nm at sucrase & maltase respectively). It increases glucagon-like peptide 1 (glp-1) secretion and also decreases food consumption in obob mice. Voglibose reduces plasma concentration of glucose, triglycerides and insulin in wistar fatty rats additionally, voglibose exhibits antidiabetic and antiobesity activity in vivo. synonyms: (1s, 2s, 3r, 4s, 5s)-5-(1, 3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl) cyclohexane-1, 2, 3, 4-tetrol cas number: 83480-29-9, mol. Formula: c10h21no7, mol.weight: 267.28 voglibose is a colourless crystalline solid powder. It is soluble to 100 mm in water and to 75 mm in dmso with melting range of 163°c to 168°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • vincristine

    vincristine

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    We are offering vincristine. Vincristine is an antitumor alkaloid isolated from vinca rosea. vincristine is an antitumor vinca alkaloid isolated from vinca rosea. It is marketed under several brand names, many of which have different formulations such as marqibo (liposomal injection) and vincasar. vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, hodgkin's disease, acute erythraemia, and acute panmyelosis. Vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone-marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy). synonyms: vincristine;vincaleukoblastine, 22-oxo-;lcr;leucristine; vleurocristine (7ci, 8ci);vincaleukoblastine, 22-oxo- (9ci);vincristine (base andor unspecified salts);vincristine ,vcr, nsc-67574, oncovin cas number: 57-22-7, mol. Formula: c46h56n4o10, mol.weight: 824.96 vincristine is a white crystalline solid. It is soluble in water, 2.27 mgl at 25 deg c (est) with melting range of 218°c to 220°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Vecuronium Bromide

    Vecuronium Bromide

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    We are offering vecuronium bromide is the bromide salt form of vecuronium, a synthetic steroid derivative of the naturally occurring alkaloids of curare with a muscle relaxant property. Vecuronium bromide competes with acetyl- choline for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This leads to skeletal muscle relaxation and paralysis. Monoquaternary homolog of pancuronium a non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents. synonyms: [(2s,3s,5s,8r,9s,10s,13s,14s,16s,17r)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-yl] acetate;bromide cas number: 50700-72-6, mol. Formula: c34h57brn2o4, mol.weight: 637.73 vecuronium bromide is white solid. It is soluble in water, dmso (128 mgml at 25° c), and ethanol (128 mgml at 25° c) with melting range of 227.2°c to 228.9°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Valdecoxib

    Valdecoxib

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    We are offering valdecoxib. Valdecoxib is a sulfonamide derivative and non-steroidal anti-inflammatory drug (nsaid) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (cox)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This nsaid does not inhibit cox-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. synonyms: 4-(5-methyl-3-phenyl-1, 2-oxazol-4-yl) benzenesulfonamide cas number: 181695-72-7, mol. Formula: c16h14n2o3s, mol.weight: 314.36 valdecoxib is white crystalline powder. It is soluble in dmso (63 mgml at 25° c), ethanol (18 mgml at 25° c), methanol, acetone, and water (0.5 mgml) with melting range of 170°c to 172°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Valacyclovir Hydrochloride

    Valacyclovir Hydrochloride

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    We are offering valacyclovir. Valacyclovir is a herpes simplex virus nucleoside analog dna polymerase inhibitor, herpes zoster virus nucleoside analog dna polymerase inhibitor & herpesvirus nucleoside analog dna polymerase inhibitor. The mechanism of action of valacyclovir is as a dna polymerase inhibitor. The chemical classification of valacyclovir is nucleoside analog. Valacyclovir is the hydrochloride salt of the l-valyl ester of the antiviral drug acyclovir. Orally administered, valacyclovir is rapidly converted to acyclovir which inhibits viral dna replication after further conversion to the nucleotide analog acyclovir triphosphate by viral thymidine kinase, cellular guanyl cyclase, and a number of other cellular enzymes.acyclovir triphosphate competitively inhibits viral dna polymerase; incorporates into and terminates the growing viral dna chain; and inactivates viral dna polymerase. The greater antiviral activity of acyclovir against herpes simplex virus (hsv) compared with varicella-zoster virus (vzv) is due to its more efficient phosphorylation by hsv thymidine kinase. synonyms: 2-[(2-amino-6-oxo-3h-purin-9-yl) methoxy] ethyl (2s)-2-amino-3-methylbutanoate cas number: 124832-26-4, mol. Formula: c13h20n6o4, mol.weight: 324.34 valacyclovir is white solid powder. It is soluble in water 2239 mgl at 25 deg c (est) with melting range of 170°c to 172°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Urofollitropin

    Urofollitropin

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    We are offering urofollitropin. Urofollitropin is a protein extract of human menopausal urine in which luteinizing hormone has been partially or completely removed. Urofollitropin represents follicle stimulating hormone from the urine. synonyms: (2s)-1-[(4r,7s,10s,13s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-13-[(2s)-butan-2-yl]-10-[(1r)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(2s)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide cas number: 97048-13-0, mol. Formula: c42h65n11o12s2, mol.weight: 980.16 urofollitropin is colourless. It is soluble in water with melting point of 55°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Triprolidine Hydrochloride

    Triprolidine Hydrochloride

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    We are offering triprolidine hydrochloride. Triprolidine hydrochloride is a component of cough and cold medicines. It may cause drowsiness. Histamine h1 antagonist used in allergic rhinitis; asthma; and urticaria. synonyms: 2-[(e)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl] pyridine; hydrochloride cas number: 6138-79-0, mol. Formula: c19h23cln2, mol.weight: 314.85 triprolidine hydrochloride is white crystalline solid powder. It is soluble in water (100 mgml), alcohol (1:1.5), and chloroform (1:

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  • Torasemide

    Torasemide

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    We are offering torasemide. Torasemide is a loop diuretic. The physiologic effect of torsemide is by means of increased diuresis at loop of henle. Torasemide is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life. synonyms: 1-[4-(3-methylanilino) pyridin-3-yl] sulfonyl-3-propan-2-ylurea cas number: 56211-40-6, mol. Formula: c16h20n4o3s, mol.weight: 348.42 torasemide is white crystalline solid powder. It is soluble in water >52.3 [ugml] with melting range of 163°c to 164°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Topiramate Liquid

    Topiramate Liquid

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    Topiramate is a sulfamate-substituted monosaccharide with anti- convulsant property. Although the mechanism of action has not been fully elucidated, topiramate antagonizeskainateampa subtype of the glutamate receptors, which are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. This antagonistic action results in stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing & decreasing propagation of synaptic impulses, thereby impedes seizure occurrences. In addition, this agent augments gamma-aminobenzoic acid (gaba) activity & thereby attenuating gabanergic inhibitory transmission.

    Type : Pure

    Purity : 100%

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  • Tolnaftate

    Tolnaftate

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    We are offering tolnaftate. Tolnaftate is a synthetic antifungal agent. Tolnaftate is a thiocar- bamate derivative with either fungicidal or fungistatic property. tolnaftate is a selective, reversible and non-competitive inhibitor of membrane-bound squalene-2, 3- epoxidase, and an enzyme involved in the biosynthesis of ergosterol. Inhibition leads to the accumulation of squalene and a deficiency in ergosterol, an essential component of fungal cell walls, thereby increasing membrane permeability, disrupting cellular organization and causing cell death. In addition, this agent may also distort the hyphae and stunts mycelial growth in susceptible fungi. synonyms: o-naphthalen-2-yl n-methyl-n-(3-methylphenyl) carbamothioate cas number: 2398-96-1, mol. Formula: c19h17nos, mol.weight: 307.41 tolnaftate is white crystalline powder. It is soluble in water 0.0000702 mgml at 25 °c with melting range of 110.5°c to 111.5°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Tizanidine Hydrochloride

    Tizanidine Hydrochloride

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    We are offering tizanidine hydrochloride. Tizanidine hydrochloride is the hydrochloride salt form of tizanidine, an imidazoline derivative structurally similar to clonidine and an adrenergic agonist with muscle relaxant property. Tizanidine stimulates alpha-2 adrenergic receptors in the central nervous system, thereby inhibiting presynaptic release of norepinephrine & increasing the inhibitory effect on alpha motor neurons & motor reflexes. tizanidine exerts some activity at the postsynaptic excitatory amino acid receptors & imidazoline receptors which may contribute to the overall reduction in facilitation of spinal motor neurons. Overall tizanidine hydrochloride causes muscle relaxation reduces spasticity & antinociceptive effects. synonyms: 5-chloro-n-(4, 5-dihydro-1h-imidazol-2-yl)-2, 1, 3-benzothiadiazol-4-amine; hydrochloride cas number: 64461-82-1, mol. Formula: c9h9cl2n5s, mol.weight: 290.17 tizanidine is a off-white to pale yellow solid. It is soluble in water (20 mgml), methanol, and dmso (100 mm) with melting point of 280°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Tinidazole

    Tinidazole

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    We are offering tinidazole. \tinidazole is a nitroimidazole antitrichomonal agent effective against trichomonas vaginalis, entamoeba histolytica, and giardia lamblia infections. Tinidazole is a nitroimidazole antimicrobial. The chemical classification of tinidazole is nitroimidazoles. Tinidazole is a 5-nitroimidazole derivative with antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized & yields nitrite anions & metronidazole. Metronidazole's nitro group in turn is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and dna strand breaks with multiple hits having an additive effect and ultimately leading to cell death. synonyms: 1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole cas number: 19387-91-8, mol. Formula: c8h13n3o4s, mol.weight: 247.27 tinidazole is a white crystalline solid powder. It is soluble in chloroform and methanol insoluble in water with melting range of 127°c to 128°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Timolol

    Timolol

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    We are offering timolol. Timolol anhydrous is a beta-adrenergic blocker. The mechanism of action of timolol anhydrous is as an adrenergic beta-antagonist. A beta-adrenergic antagonist similar in action to propranolol.the levo-isomer is the more active. Timolol has been proposed as an antihyper- tensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of migraine disorders and tremor. synonyms: (2s)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1, 2, 5-thiadiazol-3-yl) oxy] propan-2-ol cas number: 26839-75-8, mol. Formula: c13h24n4o3s, mol.weight: 316.42 timolol is a white solid powder. It is soluble in water 2.74 mgml with melting range of 71.5°c to 72.5°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Thiocolchicoside

    Thiocolchicoside

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    We are offering thiocolchicoside. Thiocolchicoside is a small molecule muscle relaxant and anti-inflammatory agent, shown to function as a competitive gabaa (gamma-aminobutyric acid type a) receptor antagonist. Thiocolchicoside is also shown to inhibit strychnine-sensitive glyr (glycine receptors)with lower potency than gabaa, and to inhibit human achr (nicotinic acetylcholine receptors) with very low relative affinity. synonyms: n-[1,2-dimethoxy-10-methylsulfanyl-9-oxo-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5h-benzo[a]heptalen-7-yl]acetamide cas number: 602-41-5, mol. Formula: c27h33no10s, mol.weight: 563.62 thiocolchicoside is a yellow solid powder. It is soluble in water, and 100% ethanol insoluble in ether, and acetone with melting range of 190°c to 198°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • terbutaline

    terbutaline

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    We are offering terbutaline. Terbutaline is a selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic. Terbutaline is a β-adrenoceptor agonist. Terbutaline is an activator of β2-ar. synonyms: 5-[2-(tert-butylamino)-1-hydroxyethyl] benzene-1, 3-diol cas number: 23031-25-6, mol. Formula: c12h19no3, mol.weight: 225.28 terbutaline is a white crystalline powder. It is soluble in ethanol and methanol with melting range of 119°c to 172°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Tenofovir

    Tenofovir

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    We are offering tenofovir. Tenofovir is an adenine analog reverse transcriptase inhibitor with antiviral activity against hiv-1 and hepatitis b. It is used to treat hiv infections and chronic hepatitis b, in combination with other antiviral agents, due to the emergence of antiviral drug resistance when it is used alone. Tenofovir anhydrous is a human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor and hepatitis b virus nucleoside analog reverse transcriptase inhibitor. The mechanism of action of tenofovir anhydrous is as a nucleoside reverse transcriptase inhibitor. The chemical classification of tenofovir anhydrous is nucleoside analog. synonyms: [(2r)-1-(6-aminopurin-9-yl) propan-2-yl] oxymethylphosphonic acid cas number: 147127-20-6, mol. Formula: c9h14n5o4p, mol.weight: 287.21 tenofovir is a white crystalline solid. It is soluble in dmso (10 mm), 1.1 eq.naoh (100 mm), water (2 mgml at 25° c), and ethanol (

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  • TEGASEROD

    TEGASEROD

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    We are offering tegaserod. Tegaserod is a serotonin-4 receptor antagonist. The mechanism of action of tegaserod is as a serotonin 4 receptor antagonists. Its use was also approved to treat chronic idiopathic constipation. synonyms: 1-[[(z)-(5-methoxyindol-3-ylidene) methyl] amino]-2-pentylguanidine cas number: 145158-71-0, mol. Formula: c16h23n5o, mol.weight: 301.39 tegaserod is a soluble in water (slightly) with melting point of 198.15°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Tazarotene

    Tazarotene

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    We are offering tazarotene. Tazarotene is a retinoid. The chemical classification of tazarotene is retinoids. Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (tig3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. synonyms: ethyl 6-[2-(4, 4-dimethyl-2, 3-dihydrothiochromen-6-yl) ethynyl] pyridine-3-carboxylate cas number: 118292-40-3, mol. Formula: c21h21no2s, mol.weight: 351.46 tazarotene is a soluble in water (partly), chloroform, dmso (>15 mgml), methanol, and ethanol (50 mm) with melting range of 97°c to 98°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Tamoxifen

    Tamoxifen

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    We are offering tamoxifen. Tamoxifen is an estrogen agonistantagonist. The mechanism of action of tamoxifen is as a selective estrogen receptor modulator one of the selective estrogen receptor modulators with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue but as an estrogen (stimulating agent) in cholesterol metabolism, bone density &cell proliferation in the endometrium.tamoxifen base is an antineoplastic nonsteroidal selective estrogen receptor modulator (serm). Tamoxifen competitively inhibits the binding of estradiol to estro- gen receptors, thereby preventing the receptor from binding to the estrogen-response element on dna. The result is a reduction in dna synthesis & cellular response to estrogen. In additiontamoxifen up-regulates the production of transforming growth factor b (tgfb), a factor that inhibits tumor cell growth & down-regulates insulin-like growth factor 1 a factor that stimulates breast cancer cell growth. synonyms: 2-[4-[(z)-1, 2-diphenylbut-1-enyl] phenoxy]-n, n-dimethyle thanamine cas number: 10540-29-1, mol. Formula: c26h29no, mol.weight: 371.51 tamoxifen is a white crystalline solid powder. It is soluble in dichloromethane with melting range of 97°c to 98°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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  • Tacrolimus

    Tacrolimus

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    Tacrolimus is a macrolide isolated from the culture broth of a strain of streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus anhydrous is a calcineurin inhibitor immunosuppressant. The mechanism of action of tacrolimus anhydrous is as a calcineurin inhibitor.Anhydrous from of tacrolimus, a macrolide isolated from streptomyces tsukubaensis. Tacrolimus binds to the fkbp-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo & prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.Tacrolimus Is A White Crystalline Solid Powder. It Is Soluble In Chloroform And Methanol With Melting Range Of 90°C TO 92°C.

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About the Company

  • Primary Business Exporters
  • Secondary Business Type Manufacturer / Wholesale Suppliers
  • Year of Establishment 1978
  • No. of Employees Below 20
  • Annual Turnover Rs. 0.5 to 2.5 Crore Approx.
  • Ownership Type Individual (Sole proprietorship)
  • GSTIN Number 27AGPPS8689E1ZF

Opening Hours

  • SUN : Closed
  • MON : 9:30 AM - 6:30 PM
  • TUE : 9:30 AM - 6:30 PM
  • WED : 9:30 AM - 6:30 PM
  • THU : 9:30 AM - 6:30 PM
  • FRI : 9:30 AM - 6:30 PM
  • SAT : 9:30 AM - 6:30 PM
Uma Brothers is Exporters of [Medicines Tonics and Drugs] - Rafoxanide, Triclabendazole, Chlorhexidine Gluconate, Diclofenac Sodium, Serratiopeptidase, [Pharmaceutical raw materials] - Sodium Glycerophosphate, Croscarmellose Sodium, Metformin hydrochloride, Sodium Starch Glycolate, ibandronate sodium, [Industrial Chemicals] - Para Toluene Sulfonic Acid, Potassium Iodide, Pvp Iodine, Propylparaben, Atorvastatin Calcium from Mumbai, Maharashtra.
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Uma Brothers

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