Pamidronate Disodium Dealers (15 products available)

• Country of Origin: India
• Strength: 30 mg
• Packaging Type: Vial
• Generic Name: Aredia
• Manufacturer: Novartis India Ltd
• Shelf Life: 24 Months
• Prescription/Non-Prescription: Non-Prescription
• Composition: Pamidronate

• Supplied By: UMA Brothers, India

We are offering pamidronate disodium is the disodium salt of the synthetic bisphospho- nate pamidronate. Although it’s mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation. Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase & bone resorption. Studies suggest that pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κb pathway activation, via the endothelial protein c receptor. synonyms: disodium; [3-amino-1-hydroxy-1-[hydroxy (oxido) phosphoryl] propyl] hydroxyphosphinate; pentahydrate cas number: 57248-88-1, mol. Formula: c3h9nna2o7p2.xh2o, mol.weight: 279.03 pamidronate disodium is white crystalline powder. It is soluble in water: 28 mgml with melting point of 300°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

• CAS No.: 57248-88-1
• Country of Origin: India
• Synonym: 3-Amino-1-hydroxy-1-phosphonopropyl phosphonic acid disodium salt
• Molecular Formula: C3H9NNa2O7P2
• Molecular Weight: 279.03
• Specifications: Available On Request
• Packing: Export Worthy Packing
• Availability: For commercial & R&D Purpose
• Color: As per standard

Jigs chemical is global Manufacturer, supplier of Pamidronate disodium salt CAS no.57248-88-1, API, active pharmaceutical ingredients, intermediates, with documentation and certification, in India, China, UK, USA, Australia, Maxico, Canada, with DMF, CEP, COS, COPP. We offer as per requirements of RND/ Development quantities or commercials, Buy high quality source with supportive technical package.   Pamidronate disodium salt CAS no.57248-88-1 API, active pharmaceutical ingredient to the pharmaceutical industry. Our Pamidronate disodium salt CAS no. 57248-88-1 is manufactured by cGMP compliant facility. Welcome to contact us for further details including current DMF status for the product . We look forward to assisting you with your research and development projects.   We offer from small R&D to commercial Quantity Pamidronate disodium salt CAS no.57248-88-1 with documentation like USDMF, EDMF, DMF (OPEN PART), DMF (CLOSED PART) CEP / COS, PMDA - JAPAN, DMF - CANADA, TGA - AUSTRALIA, , MHRA - UK, DMF - KOREA, AIFA - ITALY, TDP, HEALTH CANADA, MEDSAFE - NEW ZEALAND, , JDMF, JAPAN - AFM, DMF - CTD, DCGI, ICH, COPP, TDMF, Written Confirmation? Please contact us to send us sourcing request.

• Type: WHITE CRYSTALLINE POWDER
• CAS No.: 57248-88-1
• WHITE CRYSTALLINE POWDER: WHITE CRYSTALLINE POWDER

Pamidronate disodium is the disodium salt of the synthetic bisphospho- nate pamidronate. Although it’s mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation. Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase & bone resorption. Studies suggest that pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κb pathway activation, via the endothelial protein c receptor.