REMOVER-12 is a treatment of COVID-19. It may reduce the duration of illness. Ivermectin, an FDA approved anti-parasitic agent, was found to be an inhibitor of SARS-CoV-2 replication in the laboratory. Ivermectin, a popular anti-parasitic agent, acts on SARS-CoV-2 by preventing viral proteins from entering the host cell nucleus. Composition of REMOVER-12 : Ivermectin 12 mgIndications :
Prophylaxis in Contacts
For Prophylaxis in Health Care Workers
For Treatment of COVID-19 Positive
Mechanism of Action :Ivermectin induces inhibition of importin α/β mediated coronavirus proteins transport. It mimics the cNLS i.e. classical Nuclear Localization Signal. In general, proteins found in cytoplasm are marked with cNLS.Here Ivermectin starts functioning by:
First, Ivermectin mimics cNLS and then binds to Importin A.
Identifying by Importin A (Adaptor Protein).
This labeled protein is linked to importin B (Nuclear transport protein).
Second, Ivermectin binds directly to Importin B.
The cargo protein is transmitted to nucleus.
Dosage : 1 Tab OD for 5 days or As directed by the physician.Packaging Size : One Box of 10 Strips × 10 TabletsExpiry : 2 Years from the manufacturing dateHow to Use Amoclave 1000 : As directed by the physician.Country of Origin : IndiaManufacturing Address : Marc Lab,112, HPSIDC, Baddi, Himachal Pradesh 173205