H C Ferro Manganese
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Some preliminary magnetic resonance imaging studies have shown that manganese accumulates in the globus pallidus. Manganese causes neuronal loss and gliosis in the striatum, subthalamic nucleus, and pallidum, but little change in the substantia nigra.
Positron emission tomography (PET) scans of two welders showed abnormalities typical of idiopathic Parkinson's disease. The authors concluded that parkinsonism in welders cannot be distinguished from idiopathic Parkinson's disease, except by early age of onset.
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