MK Teknology1 Pvt. Ltd. Vikas Puri, Delhi

First principal electrophoresis zeta potential and Brownian diffusion size Measure, what you see With ZetaView® individual particle tracking, classical micro-electrophoresis and Brownian motion are presented as modern analysis tools. Auto-alignment and auto-focusing make the “Seeing is Believing” principle user friendly. By sub-volume scanning robust results of zeta potential and size histograms are derived from thousands of particles. In addition, particle concentrations can be determined by video frame assessment counting. Sample cell handling is reduced to a few handholds.

Purge or zero count filters allow the user to make a quick sanity check of the sensor before making the day’s round of monitoring. The test demonstrates there is no major problem with the instrumentation that would result in false high counts.

USE INNOVATIVE TECHNOLOGIES TO DRIVE PERFORMANCE – HIGHEST BRILLIANCE IN INDUSTRIAL QUALITY As compared to conventional technology, the WAVE systems with IPS displays offer high color accuracy and distinct color presentation. A major advantage is that the viewing angle makes hardly any difference. An IPS display provides a viewing angle of 180° in all directions with almost exactly the same color and contrast. Particularly sharp images are obtained with the PCT multi-touch display with optical bonding. We gladly design customer-specific solutions on request.

The VKL series of dilution systems according to the elector principle forms the basis for VDI guideline 3491 sheet 15. The welas® VKL dilution systems are a classic among dilution systems, as they have been successfully used throughout the world since 1984. They are characterized by a particularly long service life and easy operation. The VKL series of dilution systems deliver a temporally constant, representative dilution with the factors 10 and 100. They can easily be cascaded down to a dilution factor of 1:1,000,000. The function of the cascaded VKL systems can be quickly and clearly validated by the user on-site. Depending on the application area, the VKL systems can be configured pressure-resistant to 10 bar overpressure or made of stainless steel for aggressive aerosols. The VKL systems can be combined with all common particle counters, i.e. for suction volume flows from the VKL step of approx. 0.03 lmin to 50 lmin.

Especially for diluting liquid aerosols, the VDD dilution system offers special advantages, e.g. with the variable dilution factor and minimization of losses with large droplets. With the VDD series, the input dilution air is controlled using a mass flow controller. The dilution factor of the VDD series is infinitely variable from 1 - 10. In combination with a downstream measuring device, e.g. welas® digital or Promo®, the particle size distribution and concentration is measured with the highest accuracy. A device combination of this kind is successfully used e.g. for measuring the droplet size of coolant lubricant.

Blend Uniformity: We have developed a highly robust, maintenance free and regulatory accepted NIR method for monitoring blend uniformity, end-point detection and control of dry mixing processes. It provides an efficient alternative for thief sampling and has been successfully applied in productprocess development, up-scaling and manufacturing. In-line end-point detection and process control eliminate the need for extensive mapping of input material variability, resulting in direct efficiency benefits in development as well as in manufacturing. Additionally, the PAT application offers overall reduction in analytical resources, improved process understanding and consistent end product quality.

LOW COSTS AND LITTLE MAINTENANCE Ultra thin client technology turns a monitor into an intelligent thin client without the need for a Windows operating system. It provides extremly powerful graphics capabilities for access to server systems such as Microsoft TSE (RDP, ICA protocol and VDI) or UNIXLINUX (VNC protocol). Only a few clicks are needed to connect the monitor with ultra thin client to the server by way of the IP address. The ultra-thin client supports USB devices such as keyboard, mouse, scanner, printer, touchscreens, smartcard reader, audio etc. The ultra thin client administration software permits remote maintenance of the remote clients. SIMPLE AND CENTRAL REMOTE ADMINISTRATION In combination with the Universal Desktop Converter 2, the IGEL Thin Client represents a fully equivalent alternative to standard thin client hardware. The software is installed as operating system on PCs, Notebooks and selected thin clients and turns the hardware used into a powerful software-based, universally applicable thin client for secure access to a variety of IT infrastructures.

Unlike the AGF series, UGF 2000 has a cyclone with built-in control air. The aerosol concentration is able to be varied by a factor of 500 using the control air introduced into the cyclone. High-efficiency particulate air filters (with quality H10-U17) are tested in accordance with international conventions with an aerosol whose particle count is mainly within the so-called MPPS (Most Penetration Particle Size, dp = 0.1 – 0.3 µm) range. The UGF 2000 provides this particle size spectrum exactly and the desired concentration. Large droplets generate high mass flows and may contaminate these filters to such an extent that droplet loading causes the filters to be evaluated as better than they actually are during filter testing. Exact isokinetic sampling is not necessary when sampling particles < 2 µm. This is why the UGF 2000 system has been successfully used worldwide for HEPAULPA filter testing for over 25 years

The UGF 2000 aerosol generator is able to atomize liquids with a binary nozzle. The UGF 2000 comprises an adjustable binary nozzle for adjustment of the desired mass flow and a cyclone. Unlike the AGF series, UGF 2000 has a cyclone with built-in control air. The control air is adjusted using a micrometer screw on a needle valve. By opening this valve, the aerosol concentration is able to be reduced by a factor of approx. 500 through the addition of control air. As a result, the generator is ideally suited for testing laminar flow boxes and clean rooms with low volume flow. Startup: The compressed air is supplied to a binary nozzle via a pneumatic onoff switch and an adjustable pressure regulator. The mist of droplets generated by the nozzle flows tangentially into a cyclone. Large particles are separated here by centrifugal force and drip into a separate reservoir. The remaining droplets leave the cyclone via the so-called "immersion tube". The size spectrum of these droplets is determined on the one hand by the primary droplet spectrum generated by the nozzle, but especially by the separation characteristics of the cyclone on the other hand.

The UF-CPC 50 measures the total particle concentration of ultrafine and nanoparticles suspended in air or other carrier gases. These particles are enlarged by a condensation process in order to enable the precise determination of their number with an optical light scattering detector. The working fluid, e.g. butanol or water, is vaporized as a condensation agent. The nanoparticles to be measured are directed through the vapor atmosphere, during which the vapor condenses on the nanoparticles in a cooling zone. The condensation process is influenced by the nanoparticles themselves, as well as the working fluid, the operating temperatures, and the volume flow. In addition to their number, the UF-CPC 50 also measures the size of the droplets and provides the user with additional information concerning the condensation process. This novel and patented (German patent no.: DE 10 2005 001 992 A1) working fluid delivery system provides greater flexibility. The user is no longer limited to butanol or water but may also opt for more environmentally friendly or better suited working liquids for special applications, in addition to the butanol and water.

In addition to their number, the UF-CPC 200 also measures the size of the droplets and provides the user with additional information concerning the condensation process. This novel and patented (German patent no.: DE 10 2005 001 992 A1) working fluid delivery system provides greater flexibility. The user is no longer limited to butanol or water but may also opt for more environmentally friendly or better suited working liquids for special applications, in addition to the butanol and water.

Condensation particle counter for number concentration up to 7 • 104 particlescm3 (single count mode) and 107 particlescm3 (photometric mode) The UF-CPC 100 measures the total particle concentration of ultrafine particles and nanoparticles suspended in air or other carrier gases. These particles are enlarged by a condensation process in order to enable the precise determination of their number with an optical light scattering detector. The working fluid, e.g. butanol or water, is vaporized as a condensation agent. The nanoparticles to be measured are directed through the vapor atmosphere, during which the vapor condenses on the nanoparticles in a cooling zone. The condensation process is influenced by the nanoparticles themselves, as well as the working fluid, the operating temperatures, and the volume flow. In addition to their number, the UF-CPC 100 also measures the size of the droplets and provides the user with additional information concerning the condensation process. This novel and patented (German patent no.: DE 10 2005 001 992 A1) working fluid delivery system provides greater flexibility. The user is no longer limited to butanol or water, but may also opt for more environmentally friendly or better suited working liquids for special applications.

The Palas® universal scanning mobility particle sizer (U-SMPS) for high aerosol concentrations is available in two versions. The long classifying column (2700 model) is able to reliably determine particle size distributions of 8 to 1,200 nm. The Palas® U-SMPS system includes a classifier [defined in ISO 15900 as a differential electrical mobility classifier (DEMC), also known as a differential mobility analyzer (DMA)], in which aerosol particles are selected according to their electrical mobility and passed to the outlet. The electrical charges carried by these particles are then measured in a downstream Charme®aerosol electrometer . A major advantage of aerosol electrometers includes the fact that they enable very rapid measurements. However, this method requires a rather high number of charges. This limits the applicability to high aerosol concentrations (e.g. downstream from a combustion process or particle generator). The measurement of the charge per time unit (flow) is directly traceable to physical parameters. As a result, this method is primarily used as a reference during calibration of condensation particle counters.

U-SMPS 2700 X Universal scanning mobility particle sizer for high concentrations of 8 – 1200 nm with integrated X-ray ionization

The Palas® universal scanning mobility particle sizer (U-SMPS) for high aerosol concentrations is available in two versions. With a short classification column (1700 model), the U-SMPS is especially well suited for extremely precise measurements of particle size distributions within the range of 2 to 400 nm. The Palas® U-SMPS system includes a classifier [defined in ISO 15900 as a differential electrical mobility classifier (DEMC), also known as a differential mobility analyzer (DMA)], in which aerosol particles are selected according to their electrical mobility and passed to the outlet. The electrical charges carried by these particles are then measured in a downstream Charme®aerosol electrometer. A major advantage of aerosol electrometers includes the fact that they enable very rapid measurements. However, this method requires a rather high number of charges. This limits the applicability to high aerosol concentrations (e.g. downstream from a combustion process or particle generator). The measurement of the charge per time unit (flow) is directly traceable to physical parameters. As a result, this method is primarily used as a reference during calibration of condensation particle counters.

The Palas® universal scanning mobility particle sizer (U-SMPS) is available in two versions. With a short classification column (105011001200 models), the U-SMPS is especially well suited for extremely precise measurements of particle size distributions within the range of 4 to 600 nm. The Palas® U-SMPS system includes a classifier [defined in ISO 15900 as a differential electrical mobility classifier (DEMC) also known as a differential mobility analyzer (DMA)], in which aerosol particles are selected according to their electrical mobility and passed to the outlet. These particles are then counted by a condensation particle counter (e.g. Palas® UF-CPC). The three available UF-CPC models enable optimal single particle counting in various concentration ranges

A sub-analysis alone is often performed for the determination of the aerosol concentration in the workplace, in the environment or within an interior space. In the case of mass determinations, e.g. PM10 and PM2.5, ultrafine particles andor nanoparticles are usually not considered. However, it is precisely these tiny particles that penetrate more deeply into the human respiratory tract. The Palas U-RANGE combines a U-SMPS for nanoparticle measurements with an optical aerosol spectrometer, thus enabling automatic and continuous measurement of the particle size distribution of airborne particles between 8 nm and 40 µm. In addition, it simultaneously determines the following PM fractions: PM1, PM2.5, PM4, PM10, and TSP (PMtot). The time resolution of the system is 5 minutes, thus enabling measurement and analysis of the dynamic timing of an aerosol (e.g. during a workday). Both systems can also be used individually. The data are saved in one file when the systems are combined. The enclosed evaluation software provides an array of sophisticated data evaluation and export functions. The U-RANGE is the zenith of aerosol measurement technology with respect to measuring range. It provides optimal accuracy and reliability.

The Fidas® 200 is also equipped with a filter holder for the insertion of an absolute filter (47 or 50 mm in diameter). This enables a subsequent chemical analysis of the composition of the aerosol, for example. The U-RANGE is operated using a graphical user interface on a touch screen. The voltage in the DEMC classifier is varied continuously, resulting in higher count statistics per size channel. In addition, it enables a size resolution of up to 64 size channels per decade. The integrated data logger allows linear and logarithmic display of the measured values on the device itself. The enclosed evaluation software provides various data evaluation (extensive statistics and averaging) and export capabilities.

Test rig for testing vacuum cleaners in accordance with the standard EN 60312 With the aid of the model group TVE 3000, vacuum cleaners are tested more reliably and more cost-effectively than as per the definitions in the standard EN 60312. With the TVE 3000, it is also possible to distinguish the separation behavior of vacuum cleaners with bags and vacuum cleaners with bags and HEPA end filters reliably with with dust or as an option with salts – e.g. NaCl or KCl. The raw gas and clean gas measurements are performed virtually simultaneously. This makes it possible not only to accurately compare vacuum cleaners, but also to accurately assess the individual filter stages.

With the aid of the TVE 3000, vacuum cleaner tests can be carried out more cost-effectively than in accordance with the standard EN 60312. In addition, it is possible to distinguish the separation behavior of vacuum cleaners with bags and vacuum cleaners with bags and HEPA end filters reliably with with dust or as an option with salts – e.g. NaCl or KCl within the salt generator AGK 2000. The dust disperser RBG 1000 that is used operates much more uniformly than is required in the standard and therefore delivers an optimized dust application, which is a prerequisite for exact measurements of separation efficiency with a particle measurement device. With the particle measurement system Promo® 2000 with the aid of the welas® 2300 aerosol sensor in the clean gas, the emissions of a vacuum cleaner can be measured in accordance with the standard. As a result, not only is it possible to accurately compare vacuum cleaners, but the individual filter stages can also be reliably assessed. With the particle measurement system Promo® 3000, users have access to a high-resolution aerosol spectrometer for virtually simultaneous determination of the particle size distribution and the particle concentration in the raw gas and in the clean gas. The welas® 2070 aerosol sensor accurately determines the measurement in the raw gas, while the welas® aerosol sensor 2300 performs the measurement in the clean gas, allowing the fraction separation efficiency of vacuum cleaner bags and HEPA end filters to be performed.

Our integrateable, IT-compatible stainless steel platforms will significantly reduce your technical costs. They enjoy a long life span, which is guaranteed by an uncompromising industry design comprised exclusively of components that meet the industry’s requirements. The Systec & Solutions platforms can be retrofitted and upgraded at any time; they are compatible with all current hardware and software systems and are easy to implement into an existing IT environment.

The mobile workstation is based on ergonomic principles with easy access to all components. The stainless steel casing with protection class IP65 is GMP compliant. Optionally the system can be equipped with battery charging technology. Hardware-wise, we offer GMP compliant Monitors or Industrial PCs respectively Office Thin Clients. We gladly design customer-specific solutions on request.

DRIVEN BY INNOVATION � INDUCTIVE CHARGING TECHNOLOGY WITHOUT CABLES AND PLUGS The TROLLEY LIGHT INDUCTIVE in particular satisfies the demand for minimal space requirement coupled with the greatest possible flexibility and modularity. In conjunction with a WLAN data link, an independent power supply allows full system mobility. Independent power supply for sustained operation: Integrated batteries permit sustained operation to suit the ambient conditions. The energy transfer for the charging process of the integrated batteries is carried out inductively. The TROLLEY LIGHT INDUCTIVE is docked on a charging station at the wall, enabling charging and simultaneous operation of the IPC system without cables and plugs. The embedded WLAN allows working without network cables. The compact design requires little space. The TROLLEY LIGHT INDUCTIVE, with its completely enclosed construction, fulfills the requirements of the protection class IP65. The system is ideal for mobile operation in cleanrooms and environments with strict hygiene requirements.

Purity : Optimal for GMP conditions and cleanrooms Cordless energy transfer The energy transfer for the charging process and simultaneous operation is carried out inductively without cables and plug contacts. Etc.

ready-to-connect, mobile industrial platforms – the ideal complete system for confined rooms the mobile workstation trolley light is designed to be ergonomic and easy to use. in combination with, for example the wave 224 including a pct multi-touch display, the trolley light opens up completely new possibilities for use. the ready-for-connection, mobile workstations in uncompromising industrial design with exclusively industry-compatible components guarantee a long-term availability. hardware-wise, we offer gmp compliant monitors or industrial pcs respectively office thin clients. we gladly design customer-specific solutions on request.

PAT applications extract real time data from a process by employing fast and (mostly) non-invasive spectroscopic and optical technologies and translate recorded raw data into meaningful process information in order to control the process in real time. In a traditional (non PAT) approach process performance can only be assessed via the quality of the end product. Adequate performance of the process can therefore only be judged retrospectively, when the end product already may have to be rejected. Besides process control, PAT data can be used efficiently to increase process understanding during development, validation, transfer or routine manufacturing. PAT data can be seen as a process signature allowing for in-depth interpretation, mechanistic understanding and continuous improvement of your process. A third possibility is to employ PAT as a substitute for traditional release testing, known as Real Time Release. This approach saves laborious analytical testing and logistical efforts and shortens the cycle time of manufacturing significantly.

InProcess-LSP can provide services from consultancy up to full implementation of an application. Depending on your needs specific parts of services can be delivered. If your organization manages application development and validation activities in house, InProcess-LSP can support you in areas where you need additional expertise, and avoid additional costs for activities you manage internally. Six-Sigma: InProcess-LSP endorses the use of Six-Sigma principles for most projects. We are experienced in applying the six sigma models for process improvement and process design. Common for both approaches is the transparency in translating objectives into desired and measurable results. InProcess-LSP is experienced in applying typical related tools like DoE, Pugh Matrix, QFD, Risk Analysis, FMEA, Process Capability and (Monte Carlo) Simulation. Project structure and management: After a free of charge intake with InProcess-LSP desired next steps can be identified. For larger projects we propose to phase the project according to clear milestones in order to manage and control the project with respect to costs and outcome.

InProcess-LSP can provide services from consultancy up to full implementation of an application. Depending on your needs specific parts of services can be delivered. If your organization manages application development and validation activities in house, InProcess-LSP can support you in areas where you need additional expertise, and avoid additional costs for activities you manage internally. Six-Sigma: InProcess-LSP endorses the use of Six-Sigma principles for most projects. We are experienced in applying the six sigma models for process improvement and process design. Common for both approaches is the transparency in translating objectives into desired and measurable results. InProcess-LSP is experienced in applying typical related tools like DoE, Pugh Matrix, QFD, Risk Analysis, FMEA, Process Capability and (Monte Carlo) Simulation. Project structure and management: After a free of charge intake with InProcess-LSP desired next steps can be identified. For larger projects we propose to phase the project according to clear milestones in order to manage and control the project with respect to costs and outcome.